Scrub Typhus IgM ELISA Test Kit
The TRUSTwell Scrub Typhus IgM ELISA Test Kit is an indigenously developed product that has the following advantages over other commercial ELISA kits.
- Catalog Number: AE0620
- Brand: TRUSTwell
- Pack Size: 96 well
- Shelf Life: 12 months
- Specimen Type: Serum or Plasma
- Storage Temperature: 2-8 °C
₹18,000.00 Original price was: ₹18,000.00.₹10,500.00Current price is: ₹10,500.00.
The TRUSTwell Scrub Typhus IgM ELISA Test Kit utilizes a specific Recombinant Protein to improve sensitivity and specificity for better performance. A lateral flow chromatographic immunoassay for the simultaneous detection and IgM antibodies for Orientia tsutsugamushi (Scrub typhus) in Human Serum/ Plasma specimen. Scrub Typhus infection is caused by Orientia tsutsugamushi, transmitted to humans via the bites of infected chiggers. Among the lab test methods, IgM ELISA detects early infection with high sensitivity and throughput.
Features of Scrub Typhus IgM ELISA Test Kit:
- Highly specific to Gilliam, Kato & Karp stains.
- Highly specific to IgM detection using targeted sensitizer.
- Evaluated with a total of 1,227 positive & negative specimens across 4 geographical zones of India.
- Increased Sensitivity with higher S/Co ratio.
- Only 2-step washing protocol, reducing manual workload.
- Minimal assay time of 70 minutes.
- 18 months longer shelf life.
Intended use of Scrub Typhus IgM ELISA Test Kit:
The TRUSTwell Scrub Typhus IgM ELISA is a solid-phase enzyme-linked immunosorbent assay for the qualitative detection of Scrub Typhus IgM antibodies in human serum or plasma. It is intended for professional use only as an aid in the diagnosis of infection with Scrub Typhus. Any reactive specimen with the TRUSTwell Scrub Typhus IgM ELISA Test must be confirmed with alternative testing method(s) and clinical findings.
Introduction of TRUSTwell Scrub Typhus IgM ELISA Test Kit:
TRUSTwell Scrub Typhus(ST) is caused by infection with the obligate, intracellular, gram-negative bacterium Orientia tsutsugamushi. Globally, over one billion people are at risk for Scrub Typhus and an estimated one million cases occur annually. Karp strain is predominant in India other than that Kato, Gilliam, Boryong, Kawasaki, and other 30 are the most habitual serotypes of O.tsutsugamushi. The World Health Organization has dubbed Scrub Typhus one of the world’s most underdiagnosed diseases that often require hospitalization highlighting the necessity for a better understanding of the vectors, outbreaks, and pathogenesis associated with this potentially fatal organism that has been linked to human cases both within and beyond its previously recognized region of endemicity.
In India, Scrub Typhus is a major public health threat, and it has been reported from Tamilnadu, Andhra Pradesh, Karnataka, and Kerala in the South, Himachal Pradesh, Uttaranchal, Jammu, and Kashmir in the North, Meghalaya, Assam, and Nagaland in the North-East, West Bengal and Bihar in the East, and Maharashtra and Rajasthan in the West (Devasagayam et al., 2021). While Scrub Typhus is confined geographically to the Asia Pacific region, and mortality rates for Scrub Typhus range from < 1% to 50% it may increase depending upon the age. It also depends on proper antibiotic treatment, the status of the individual infected, and the strain of O. tsutsugamushi encountered (Kala et al., 2020). In addition, a few cases have tested positive for IgM antibodies for scrub typhus from Sikkim, Darjeeling, Manipur.
ELISA detects IgM antibodies against the 56kDA antigen, the major immunodominant protein located on its cell envelope. (Martina L.Jones et al., 2007) Sera from 95–99% of patients with a history of scrub Typhus react strongly with this protein, which reflects the abundance of the molecule on the cell surface and its high immunogenicity. (Sheng Ni et al., 2005) After the onset of symptoms, the IgM antibody titers increased gradually over 2–3 weeks and peaked at about 4 weeks. The onset of the disease is characterized by fever, headache, myalgia, cough, and gastrointestinal symptoms. The TRUSTwell Scrub Typhus IgM utilizes recombinant Scrub Typhus antigens for the detection of IgM antibodies associated with the Scrub Typhus.
TRUSTwell Scrub Typhus IgM ELISA Test Kit:
The Scrub Typhus Detect™ IgM ELISA Test Kit is an enzyme-linked immunosorbent assay (ELISA) system designed for the detection of IgM antibodies in human serum to Orientia tsutsugamushi (formerly known as Rickettsia).
- Purpose:
- Detects IgM antibodies were specific to Scrub Typhus (caused by Orientia tsutsugamushi).
- Scrub Typhus is a tropical disease transmitted by chigger mites.
- Early diagnosis is crucial for timely treatment with antibiotics.
- Sample Type: It works with human serum.
- Detection Method: Utilizes a colorimetric technique based on the ELISA.
- Clinical Significance:
- Scrub Typhus can cause fever, headache, muscle pain, and skin lesions (eschar).
- Cross-reactivity with other infections may occur, so results should be interpreted carefully.
Weight | 0.450 kg |
---|---|
Dimensions | 18 × 12 × 12 cm |
Promotional Information
Related products
TSH ELISA Kit
Syphilis Ab ELISA Kit
Malaria Ag ELISA Kit
Vitamin D (Total) ELISA Kit
HEV IgM ELISA Kit
HCV IgG ELISA Kit
TRUSTwell Ferritin ELISA Kit
HBsAg ELISA Kit
Leptospira IgM ELISA Kit
CHIK IgM ELISA Kit
Total T3 ELISA Kit
FAST SHIPPING
We offered fast delivery depends on stock availability and location.
ORDER RETURN
Return within 3 days
ORDER RETURN Return within 3 days with proper storage condition If for any reason, you want to return the product, you are free to return it at the time of delivery. However, in such return cases the cancellation rules will be applicable. The return request would need to be sent through the e-mail from your registered e-mail ID, at ecommerce@athenesedx.com, or by contacting us on our Sales Support Phone No +91 7397238924, mentioning order details being mandatory.
Reviews
There are no reviews yet